Temperature control
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Temperature Control > Microscope Objective Heaters


Objective Heater - Warmer Upgrade

A thin flexible polyimide heater for any microscope objective. Used with oil or water immersion optics. Built-in temperature sensor. Easy to attach and remove. Simply wrap the heater around objective and secure with included Velcro tape. The heater is usually attached to a cylindrical surface of the objective, closer to the sample. The controller stores two settings in its memory for different size objectives. Sample publications.

Specifications:

Dimensions:

0.5/0.25in. wide x 5/10in long (around objective surface)

Temperature stability:

0.01°C, self-adjusting, required for sensitive applications: nano/piezo positioning or confocal imaging

Dual overheating protection:

regulated power output down to 0W; settings eliminate temperature overshoot; adjustable temperature threshold

Easy to install:

Fits any objective



Click on catalog numbers below to purchase online.

Required accessories: temperature controllers.

Download PDF manual.

Download PDF catalog.

The picture below demonstrates high temperature stability provided by the heater. This is a temperature recording from TC-HLS objective heater. Most of the data points are between 0.01°C deviation from 30°C set level. The cursor is placed at 29.99°C level. The data points were obtained every second.


Bioscience Tools
ph: 877-853-9755,
fax: 866-533-7490
email: info@biosciencetools.com


PRICES AND OPTIONS

TC-HLS-05

$495

Objective Heater Upgrade, 0.5x5in.

TC-HLS-025

$495

Objective/Syringe Heater Upgrade, 0.25x10in.

MTC-HLS-025

$1,490

Temperature controller TC-1-100S with Objective Heater, 0.5x5in, connecting cable and power supply.


Sample publications:
41 Validity of Single Fluorescent Molecule to Report Local Dynamics of a Polymer Matrix: The Effect of Molecular Architecture. Macro- Molecular Chemistry and Physics, Volume 224, Issue 21 November 2023;
40 Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter. GeroScience, Volume 45, pages 1491–1510, (2023);
39 Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation. eLife, July 25, 2023;
38 Stress accumulation by confined ice in a temperature gradient. PNAS, July 29, 2022;
37 Adhesive Tape Microfluidics with an Autofocusing Module That Incorporates CRISPR Interference: Applications to Long-Term Bacterial Antibiotic Studies. ACS Sens. 2019, 4, 2638−2645;
36 Controlling Kinetic Pathways in Demixing Microgel-Micelle Mixtures. Langmuir, 39(3), 2023;
35 Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation. SAGE Jornal, 2022;
34 Addressing challenges in the removal of unbound dye from passively labelled extracellular vesicles. Nanoscale Adv., 2022, 4, 226-240;
33 Programming Directed Motion with DNAGrafted Particles. ACS Nano 2022, 16, 9195−9202;
32 Baseline oxygen consumption decreases with cortical depth. PLOS Biology, October 27, 2022;
31 Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion. Journal of Cerebral Blood Flow & Metabolism 2019;
30 Dynamic Transition States of ErbB1 Phosphorylation Predicted by Spatial Stochastic Modeling. Biophysical Journal 105(6) 1533–1543 2013;
29 The role of diffusion and membrane topography in the initiation of high affinity IgE receptor signaling. 5-1-2011;
28 Microscopic Quantification of Oxygen Consumption across Cortical Layers. bioRxiv - Neuroscience, October 14 2021;
27 Size homeostasis in adherent cells studied by synthetic phase microscopy. PNAS September 24, 2013;
26 Controlling phase separation in microgel-polymeric micelle mixtures using variable quench rates. arXiv:2104.04022v1 8 Apr 2021;
25 Addressing challenges in the removal of unbound dye from passively labelled extracellular vesicles. Nanoscale Adv., 2022, 4, 226-240;
24 Direct observation of individual tubulin dimers binding to growing microtubules eLife 2019; 8;
23 More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction eLife 2019; 8;
22 Spatial Temporal Analysis of Fieldwise Flow in Microvasculature J. Vis. Exp. (153), (2019);
21 FLIM reveals alternative EV-mediated cellular up-take pathways of paclitaxel Journal of Controlled Release 2018, 284, 133-143;
20 Imaging and Spectroscopic Analysis of Living Cells Methods in Enzymology, 2012;
19 Direct observation of individual tubulin dimers binding to growing microtubules bioRxiv, Sep. 14, 2018;
18 Fluorescence Lifetime Microscopy of Tumor Cell Invasion, Drug Delivery, and Cytotoxicity. Methods in Enzymology Volume 504, 2012, Pages 109-125;
17 Using DNA strand displacement to control interactions in DNA-grafted colloids. Soft Matter, 2018, 14, 969;
16 Detection of Site-dependent Segmental Mobility of Polymer. Journal of Polymer Science, 2017, 35(12): 1488-1496;
15 Examining dynamics in a polymer matrix by single molecule fluorescence probes of different sizes. Soft Matter, 2016,12, 7299-7306;
14 MICROSTRUCTURE AND PHASE BEHAVIOR IN COLLOIDS AND LIQUID CRYSTALS. University of Pennsylvania;
13 COMPOUNDS THAT BIND DYSTROGLYCAN AND USES THEREOF. United States Patent Application 20150374845;
12 Effects of cytoskeletal disruption on transport, structure, and rheology within mammalian cells. PHYSICS OF FLUIDS 19, 103102 2007;
11 Scanning Electrochemical Microscopy of Individual Pancreatic Islets. Journal of The Electrochemical Society, 163 (4) H3077-H3082 (2016);
10. Elastic Instability of a Crystal Growing on a Curved Surface. 7 February 2014, Science 343, 634 (2014);
9 Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers. November 15, 2014 J Cell Sci 127, 4894-4903;
8 Investigating G protein-coupled receptor endocytosis and trafficking by TIR-FM. Methods Mol Biol. 2011; 756: 325–332;
7, 6, 5, 4, 3, 1, 2.