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We can also produce custom computerized and mechanical items to meet your needs and requirements.

Product news - recently upgraded items:

cooling stage for slides Gas flow controller, PC-MI
The controller is used to deliver gas mixture inside any custom enclosures and miniature incubators. Connects to a cylinder with compressed pre-mixed gas (5% CO2 for example). The output connects directly to a gas port of the incubator or a humidifier. The controller regulates gas output to provide continuous slow stream of gas mixture, to replace residual gases inside the incubator, up to 1000 SCCM flow rate. Simple to use. Can be adjusted to fill incubators of different volumes.


cooling stage for slides Low Profile Cooling & Heating stage for Slides and Chambered Coverglasses, 15mm aperture
This low profile heating/cooling stage was designed to fit inside 128x86mm holders for standard multi-well plates. Can be used with: custom devices, disposable slides and coverglasses. Positioned on both sides threaded #4-40 holes can be used to mount optional IMA-MH tubing and probes holders. The cooling area is 29x79x1mm (to fit standard slides). Reduced aperture of 15mm diameter, in addition to improved temperature control, allows to use smaller samples.


cooling stage for Petri dishes Low Profile Cooling & Heating stage for Petri dishes and coverglasses
This low profile heating/cooling stage was designed to fit inside 128x86mm holders for standard multi-well plates. Can be used with 35mm Petri dishes and different size coverglasses. Positioned on both sides threaded #4-40 holes can be used to mount optional IMA-MH tubing and probes holders.


Time lapsed imaging Miniature incubators - CO2, O2 and temperature controlled microscope stages
Extended variety of heated mini-incubators for long term time lapse imaging of live cell samples to fit on any microscope. Options for any size Petri dishes, slides, coverslips and custom fluidics devices are available. Improved CO2 and hypoxia controller. Upgraded easy to use high stability precision 2-channel temperature controller TC-1-100i with rs232 port (can be used with USB adapter).


Automated liquid handling Programmable liquid perfusion/injectors/spritzers with precision timers
Complete 8/16-channel systems based on a computerized valve controllers with optional built-in pressure pumps. Front touch display allows to program up to 16 step sequences (32 step if automatic "wash" is used), including continuous loops. This is an ideal instrument to generate automated dose-response curves or any other protocols that require automatic liquid handling. The systems can be also controlled using digital and analog signals, manual remote, or through a computer rs232 port.


BIOSCIENCE TOOLS
Ph: 877-853-9755,
Fax: 866-533-7490
Email info@biosciencetools.com
References
Temperature control:
245 Functional Single-Cell Proteomics: Technology and Biological Applications. Experimental Neurology Volume 393, November 2025;
244 Endonuclease G promotes hepatic mitochondrial respiration by selectively increasing mitochondrial tRNAThr production. PNAS January 3, 2025;
243 Cell-generated mechanical forces play a role in epileptogenesis after injury. Experimental Neurology Volume 393, November 2025;
242 Opsin 5 mediates violet light-accelerated wound healing in mammalian corneas. Cell Rep. 2025 Jul 22;44(8);
241 The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots. Advanced Science Volume12, Issue31 August 21, 2025;
240 Ongoing loss of viable neurons for weeks after mild hypoxia-ischaemia. Brain Communications, Volume 7, Issue 2, 2025;
239 Single molecule spectrum dynamics imaging with 3D target-locking tracking. Nature Communications volume 16, 2025;
238 Nanotip Acetylcholine Biosensor Reveals Cholinergic Differentiated SH-SY5Y Cells Release Partial Vesicle Content During Exocytosis. chemrxiv December 2025;
237 Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells. Nature Biotechnology volume 43, pages960–970 (2025);
236 Sperm hyperactivation drives a circling-and-wandering migration strategy. bioRxiv July 05, 2025;
235 In vivo mapping organellar metabolism by optical-boxcar enhanced fluorescence-detected mid-infrared photothermal microscopy. ResearchGate April 2025;
234 Brief disruptions in capillary flow result in rapid onset of hypoxia. Neurophotonics, Vol. 12, Issue S2, August 2025;
233 Shallow-angle intracranial cannula for repeated infusion and in vivo imaging with multiphoton microscopy. Neurophotonics. 2025 Mar 25;12(2);
232 Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis. Alzheimers & Dementia Volume21, Issue3 March 2025;
231 Diurnal differences in cerebral microvascular blood flow and oxygen delivery across brain regions in awake mice. Neurophotonics, Vol. 13, Issue 1, January 2026;
230 Global hypoperfusion leads to a mismatch in oxygen delivery and consumption in the cerebral watershed area. bioRxiv June 17, 2025;
229 Biocompatibility assay of cellular behavior inside a leaf-inspired biomimetic microdevice at the single-cell level. RSC Adv., 2017, 7, 32710;
228 Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation. Cellular and Molecular Bioengineering, Vol. 6, No. 2, June 2013;
227 Genetic identification of three CITES-listed sharks using a paper-based Lab-on-a-Chip (LOC). PLOS ONE, April 4, 2024;
226 Ongoing loss of viable neurons for weeks after mild perinatal hypoxia-ischemia. bioRxiv December 20, 2024;
225 Single molecule spectrum dynamics imaging with 3D target-locking tracking. bioRxiv, September 26, 2024;
224 Hour-long, kilohertz sampling rate 3D single-virus tracking in live cells enabled by StayGold fluorescent protein fusions. bioRxiv, March 15, 2024;
223 Measuring and modeling the dynamics of mitotic error correction. PNAS 2024 Vol. 121 No. 25;
222 Modifying membrane potential synchronously controls the somite's formation periodicity and growth. Developmental Biology, Volume 517, January 2025, Pages 317-326;
221 Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells. Nature, 14 August 2024;
220 The Division Defect of a Bacillus subtilis minD noc Double Mutant Can Be Suppressed by Spx-Dependent and Spx-Independent Mechanisms. Journal of Bacteriology, Vol. 203, No. 18, 20 August 2021;
219 Automated Five-Dimensional Single Particle Tracking by Bifocal Parallax Dark-Field Microscopy with Electronic Tunable Lens. Anal. Chem. 2024, 96, 1, 1–5;
218 Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos. J. Physiology, Volume602, Issue4, 15 February 2024 Pages 597-617;
217 Temperature-Responsive Structurally Colored Fibers via Blend Electrospinning. ACS Appl. Polym. Mater. 2023, 5, 4, 3065–3078;
216 Case II diffusion of water in Na2O–3SiO2 glass: Constant tensile stress gradient at the diffusion interface. Applied Glass Science, Volume14, Issue2 April 2023;
215 A Laser-Driven Microrobot for Thermal Stimulation of Single Cells. Advanced Healthcare materials, Volume 12, Issue 26 October 18,2023;
214 Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies. bioRxiv, January 12, 2023;
213 Chemotherapy for pain: reversing inflammatory and neuropathic pain with the anticancer agent mithramycin A. PAIN 165(1):p 54-74, January 2024;
212 Degradation Kinetics of Disulfide Cross-Linked Microgels: Real-Time Monitoring by Confocal Microscopy. Gels. 2023 Oct; 9(10): 782;
211 Resveratrol Preconditioning Protects Against Ischemia-Induced Synaptic Dysfunction and Cofilin Hyperactivation in the Mouse Hippocampal Slice. Neurotherapeutics Volume 20, Issue 4, July 2023, Pages 1177-1197;
210 Redox differences between rat neonatal and adult cardiomyocytes under hypoxia. Free Radical Biology and Medicine, Volume 211, 1 February 2024, Pages 145-157;
209 Hydrogen peroxide is not generated intracellularly in human neural spheroids during ischemia-reperfusion. Free Radical Biology and Medicine Volume 212, 20 February 2024, Pages 234-240;
208 Hyperglycemia exacerbates ischemic stroke not through increased generation of hydrogen peroxide. Free Radical Biology and Medicine, Volume 208, 1 November 2023, Pages 153-164;
207 A Dynamic Balance between Neuronal Death and Clearance in an in Vitro Model of Acute Brain Injury. Journal of Neuroscience 23 August 2023, 43 (34) 6084-6107;
206 OrganoidChip facilitates hydrogel-free immobilization for fast and blur-free imaging of organoids. Nature, 11268 (2023);
205 Thermogenetic control of Ca2+ levels in cells and tissues. bioRxiv, March 22, 2023;
204 Analysis of Mouse Brain Sections by Live-cell Time-lapse Confocal Microscopy. Bio-protocol, 05 Apr 2023, 13(7);
203 Protocol to culture and image pancreatic ductal adenocarcinoma tumor slices to study T cell migration. STAR Protocols, Volume 4, Issue 1, 17 March 2023, 102135;
202 Validity of Single Fluorescent Molecule to Report Local Dynamics of a Polymer Matrix: The Effect of Molecular Architecture. Macro- Molecular Chemistry and Physics, Volume 224, Issue 21 November 2023;
201 Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter. GeroScience, Volume 45, pages 1491–1510, (2023);
200 Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation. eLife, July 25, 2023;
199 Exosome secretion kinetics are controlled by temperature. Biophysical J. Volume 122, Issue 7, 4 April 2023, Pages 1301-1314;
198 Optical sensing based on phase interrogation with a Young’s interference hologram using a digital micromirror device. Optics Express Vol. 32, Issue 3, pp. 3647-3659 (2024);
197 LONG-TERM MEMORY RULES WITHIN THE FEEDING NEURAL CIRCUIT OF THE MARINE SNAIL APLYSIA CALIFORNICA. 2022;
196 A novel in vitro analog expressing learning-induced cellular correlates in distinct neural circuits. Cold Spring Harbor Laboratory Press, February 15, 2022;
195 A microfluidic approach for forward design of modular cell-free genetic networks. 2022;
194 PHOTOELASTIC ANALYSIS OF RESIDUAL STRESS ARISING FROM WATER INTERACTION AT GLASS SURFACES. 2022;
193 Dynamin Action at the Final Stage of Clathrin-Mediated Endocytosis. Nature, 12 Jul, 2021;
192 Stress accumulation by confined ice in a temperature gradient. PNAS, July 29, 2022;
191 Adhesive Tape Microfluidics with an Autofocusing Module That Incorporates CRISPR Interference: Applications to Long-Term Bacterial Antibiotic Studies. ACS Sens. 2019, 4, 2638−2645;
190 Controlling Kinetic Pathways in Demixing Microgel−Micelle Mixtures. Langmuir, 39(3), 2023;
189 Investigating Spatiotemporal Kinetics, Dynamics, and Mechanism of Exosome Release. University of Denver Digital Commons, 2022;
188 In Vivo Wireless Brain Stimulation via Non-invasive and Targeted Delivery of Magnetoelectric Nanoparticles. Neurotherapeutics volume 18, pages2091–2106 (2021);
187 Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation. SAGE Jornal, 2022;
186 Mechanical morphotype switching as an adaptive response in mycobacteria. bioRxiv, April 7, 2022;
185 Addressing challenges in the removal of unbound dye from passively labelled extracellular vesicles. Nanoscale Adv., 2022, 4, 226-240;
184 Programming Directed Motion with DNAGrafted Particles. ACS Nano 2022, 16, 9195−9202;
183 A microfluidic optimal experimental design platform for forward design of cell-free genetic networks. Nature Communications, 13, 2022;
182 Ultrasound Mediated Cellular Deflection Results in Cellular Depolarization. Advanced Science, Volume 9, Issue2, January 14, 2022;
181 Baseline oxygen consumption decreases with cortical depth. PLOS Biology, October 27, 2022;
180 A compact microscope for voltage imaging. Journal of Optics, Volume 24, Number 5, 2022;
179 On-site genetic analysis for species identification using lab-on-a-chip. Ecol Evol. 2021 Feb; 11(4): 1535–1543;
178 Developing Analysis Protocols for Monitoring Intracellular Oxygenation using Fluorescence Lifetime Imaging of Myoglobin-mCherry. Methods in Molecular Biology, 01 Jan 2021, 2304:315-337;
177 In vivo dynamics of acidosis and oxidative stress in the acute phase of an ischemic stroke in a rodent model. j.redox.2021.102178;
176 Integrated functional neuronal network analysis of 3D silk-collagen scaffold-based mouse cortical culture. STAR Protocols Volume 2, Issue 1, 19 March 2021, 100292;
175 MAGNETO-ELECTRIC NANOPARTICLES COBALT FERRITE (CoFe2O4) – BARIUM TITANATE (BaTiO3) FOR NON-INVASIVE NEURAL MODULATIONS. September 2020;
174 A compact microscope for voltage imaging. Journal of Optics, Volume 24, Number 5 2022;
173 Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion. Journal of Cerebral Blood Flow & Metabolism 2019;
172 Dynamic Transition States of ErbB1 Phosphorylation Predicted by Spatial Stochastic Modeling. Biophysical Journal 105(6) 1533–1543 2013;
171 The role of diffusion and membrane topography in the initiation of high affinity IgE receptor signaling. 5-1-2011;
170 Microscopic Quantification of Oxygen Consumption across Cortical Layers. bioRxiv - Neuroscience, October 14 2021;
169 Size homeostasis in adherent cells studied by synthetic phase microscopy. PNAS September 24, 2013;
168 Dynamin Action at the Final Stage of ClathrinMediated Endocytosis. Research Square February 5th, 2021;
167 LASER-ASSISTED HEA ASER-ASSISTED HEATING OF A PL TING OF A PLASMONIC N ASMONIC NANOFLUID IN A UID IN A MICROCHANNEL. 2013;
166 Noc Corrals Migration of FtsZ Protofilaments during Cytokinesis in Bacillus subtilis. mBio January/February 2021 Volume 12 Issue 1;
165 Ultrasound Mediated Cellular Deflection Results in Cellular Depolarization. Adv. Sci. 2022, 9, 2101950;
164 Controlling phase separation in microgel-polymeric micelle mixtures using variable quench rates. arXiv:2104.04022v1 8 Apr 2021;
163 Addressing challenges in the removal of unbound dye from passively labelled extracellular vesicles. Nanoscale Adv., 2022, 4, 226-240;
162. Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea; Investigative Ophthalmology & Visual Science June 2020, Vol.61, 37.
161. Monitoring contractility in cardiac tissue with cellular resolution using bio integrated microlasers
160. Non-obstructive intracellular nanolasers; NATURE COMMUNICATIONS (2018) 9:4817
159. Single cell-based fluorescence lifetime imaging of intracellular oxygenation and metabolism; Redox Biol. 2020 Jul; 34: 101549
158. MAGNETO-ELECTRIC NANOPARTICLES COBALT FERRITE (CoFe2O4) – BARIUM TITANATE (BaTiO3) FOR NON-INVASIVE NEURAL MODULATIONS
157. Monitoring contractility in cardiac tissue with cellular resolution using biointegrated microlasers; University of Dundee 2020
156. Impaired Glutamate Receptor Function Underlies Early Activity Loss of Ipsilesional Motor Cortex after Closed-Head Mild Traumatic Brain Injury; J. Neurotrauma January 25, 2021
155. In vivo contactless brain stimulation via non-invasive and targeted delivery of magnetoelectric nanoparticles; bioRxiv May 31, 2020
154. Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA; NATURE COMMUNICATIONS (2020) 11:983
153 Linker-Mediated Phase Behavior of DNA-Coated Colloids. PHYSICAL REVIEW X 9, 041054 (2019);
152 Correlating Live Cell Viability with Membrane Permeability Disruption Induced by Trivalent Chromium. ACS Omega. 2019 Jan 31; 4(1): 2142–2151;
151 Genetically encoded FRET probes for direct mapping and quantification of intracellular oxygenation level via fluorescence lifetime imaging. SPIE 22 February 2019;
150 An automated microfluidic device for time-lapse imaging of mouse embryonic stem cells. Biomicrofluidics 13, 054102 (2019);
149 A Human Organotypic Microfluidic Tumor Model Permits Investigation of the Interplay between Patient-Derived Fibroblasts and Breast Cancer Cells. Cancer Research April 16, 2019;
148 The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state;
147 Shadow enhancers suppress input transcription factor noise through distinct regulatory logic. bioRxiv 2019;
146 Thermal Effects on the Crystallization Kinetics, and Interfacial Adhesion of Single‐Crystal Phase‐Change Gallium. Advanced Materials 03 February 2020;
145 Soft crystal martensites: An in situ resonant soft x-ray scattering study of a liquid crystal martensitic transformation. Science Advances 27 Mar 2020;
144 The Min System Disassembles FtsZ Foci and Inhibits Polar Peptidoglycan Remodeling in Bacillus subtilis. mBio 2019;
143 Reversible temperature-controlled gelation in mixtures of pNIPAM microgels and non-ionic polymer surfactant. Soft Matter Issue 42, 2019;
142 Overlapping and essential roles for molecular and mechanical mechanisms in mycobacterial cell division Nature Letter Published: 21 October 2019;
141 Direct observation of individual tubulin dimers binding to growing microtubules eLife 2019; 8;
140 More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction eLife 2019; 8;
139 Spatial Temporal Analysis of Fieldwise Flow in Microvasculature J. Vis. Exp. (153), (2019);
138. Intracellular oxygen mapping using a myoglobin-mCherry probe with fluorescence lifetime imaging J. Biomed. Opt. 23(10), 107001 (2018)
137 Unique Hydrophobic Extension of the RGS2 Amphipathic Helix Domain Imparts Increased Plasma Membrane Binding and Function Relative to Other RGS R4/B Subfamily Members. The Journal of Biological Chemistry November 9, 2007, 282, 33064-33075.;
136 Micro-Bullet Assembly: Interactions of Oriented Dipoles in Confined Nematic Liquid Crystal. Liquid Crystals Vol. 00, No. 00, July 2012, 1–13;
135 Micropipette Aspiration of Oocytes to Assess Cortical Tension. Methods in Molecular Biology, vol. 1818 (2018);
134 Pathogen-Related Differences in the Abundance of Presented Antigen Are Reflected in CD4+ T Cell Dynamic Behavior and Effector Function in the Lung J Immunol 15 January 2014;
133 FLIM reveals alternative EV-mediated cellular up-take pathways of paclitaxel. Journal of Controlled Release 2018, 284, 133-143;
132 Imaging and Spectroscopic Analysis of Living Cells. Methods in Enzymology, 2012;
131 Direct observation of individual tubulin dimers binding to growing microtubules. bioRxiv, Sep. 14, 2018;
130 Spectroscopic THz near-field microscope. Optics Express Vol. 16, Issue 5, pp. 3430-3438 (2008);
129 Infrared neural stimulation induces intracellular Ca2+ release mediated by phospholipase C. J Biophotonics Volume 11, Issue 2 February 2018;
128 Rhodamine B as an optical thermometer in cells focally exposed to infrared laser light or nanosecond pulsed electric fields. Biomedical Optics Express Vol. 6, Issue 10, pp. 4105-4117 (2015);
127 The Ubiquitin-like Protein PLIC-2 Is a Negative Regulator of G Protein-coupled Receptor Endocytosis. Mol. Biol. Cell March 1, 2008 vol. 19 no. 3 1252-1260;
126 IH current generates the afterhyperpolarisation following activation of subthreshold cortical synaptic inputs to striatal cholinergic interneurons. J Physiol 587.24 (2009) pp 5879–5897;
125 2,2,2-Trichloroethanol activates a non-classical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery. JPET December 2, 2009;
124 Directed self-assembly of liquid crystalline blue-phases into ideal single-crystals. Nature communications 2041-1723 Jun 2017 ;
123 Intracellular temperature mapping with fluorescence-assisted photoacoustic-thermometry. Appl. Phys. Lett. 102, 193705 (2013);
122 Mesoscale martensitic transformation in single crystals of topological defects. PNAS September 5, 2017 11207;
121 Division site selection linked to inherited cell surface wave troughs in mycobacteria . Nature Microbiology VOLUME: 2 ARTICLE NUMBER: 17094 2017;
120 The Functional Activity of the Human Serotonin 5-HT1A Receptor Is Controlled by Lipid Bilayer Composition. Biophysical J. Volume 110, Issue 11, 7 June 2016, Pages 2486-2495;
119 Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse. J. Neurophysiology Volume 117,Issue 1 January 2017;
118 Fluorescence Lifetime Microscopy of Tumor Cell Invasion, Drug Delivery, and Cytotoxicity. Methods in Enzymology Volume 504, 2012, Pages 109-125;
117 Using DNA strand displacement to control interactions in DNA-grafted colloids. Soft Matter, 2018, 14, 969;
116 Detection of Site-dependent Segmental Mobility of Polymer. Journal of Polymer Science, 2017, 35(12): 1488-1496;
115 CbtA toxin of Escherichia coli inhibits cell division and cell elongation via direct and independent interactions with FtsZ and MreB. PLoS Genet 13 (9) 2017;
114 EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis. Circulation. 2017;136:566-582;
113 Effect of suberoylanilide hydroxamic acid (SAHA) on breast cancer cells within a tumor–stroma microfluidic model. Integrative Biology 12, 2017;
112 Biocompatibility assay of cellular behavior inside a leaf-inspired biomimetic microdevice at the single-cell level. RSC Adv., 2017, 7, 32710;
111 Time-Lapse Monitoring of DNA Damage Colocalized With Particle Tracks in Single Living Cells. Int J Radiat Oncol Biol Phys. 2016 Sep 1;96(1):221-7;
110 Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment. Sci Rep. 2016; 6: 34094.;
109 Three dimensional time-gated tracking of non-blinking quantum dots in live cells;
108 Examining dynamics in a polymer matrix by single molecule fluorescence probes of different sizes. Soft Matter, 2016,12, 7299-7306;
107 Role of T-Type calcium channels in a cellular model of stroke;
106 Enhanced Directional Migration of Cancer Stem Cells in 3D Aligned Collagen Matrices. Biophysical Journal Volume 112, Issue 5, p1023–1036, 14 March 2017;
105 Vascular Dysfunction in Pneumocystis-Associated Pulmonary Hypertension Is Related to Endothelin Response and Adrenomedullin Concentration. The American Journal of Pathology, Vol. 186, No. 2, February 2016;
104 Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses. Neuroscience. 2014 June 20; 271: 45–55;
103 Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic ί Cells. The Journal of Biological Chemistry 290, 21376-21392. August 28, 2015;
102 Sensing cisplatin-induced permeation of single live human bladder cancer cells by scanning electrochemical microscopy . Analyst, 2015,140, 6054-6060;
101 Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nat Commun. 2016; 7: 10312;
100 Bacillus subtilis chromosome organization oscillates between two distinct patterns. PNAS September 2, 2014 vol. 111 no. 35;
99 Global Deletion of Ankrd1 Results in a Wound-Healing Phenotype Associated with Dermal Fibroblast Dysfunction. The American Journal of Pathology, Vol. 185, No. 1, January 2015;
98 Mitochondrial Ca2+ Uptake from Plasma Membrane Cav3.2 Protein Channels Contributes to Ischemic Toxicity in PC12 Cells. Science Open, 18 March 2013;
97 MICROSTRUCTURE AND PHASE BEHAVIOR IN COLLOIDS AND LIQUID CRYSTALS. University of Pennsylvania;
96 COMPOUNDS THAT BIND DYSTROGLYCAN AND USES THEREOF. United States Patent Application 20150374845;
95 Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis. Mol. Biol. Cell January 1, 2010 vol. 21 no. 1 165-176;
94 Effects of cytoskeletal disruption on transport, structure, and rheology within mammalian cells. PHYSICS OF FLUIDS 19, 103102 2007;
93 Vector frequency-comb Fourier-transform spectroscopy for characterizing metamaterials. New Journal of Physics, Volume 10, December 2008;
92 Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses. Neuroscience. 2014 June 20; 271: 45–55;
91 REGAINING TAXOL SENSITIVITY IN CHEMORESISTANT OVARIAN CANCER CELLS. Georgia Institute of Technology May 2015;
90 Scanning Electrochemical Microscopy of Individual Pancreatic Islets. Journal of The Electrochemical Society, 163 (4) H3077-H3082 (2016);
89 Droplet-based electro-coalescence for probing threshold disjoining pressure. Lab on a Chip, 2015, v. 15 n. 9, p. 2018-2024;
88 Global Deletion of Ankrd1 Results in a Wound-Healing Phenotype Associated with Dermal Fibroblast Dysfunction. The American Journal of Pathology Volume 185, Issue 1, January 2015, Pages 96–109;
87 Rhodamine B as an optical thermometer in cells focally exposed to infrared laser light or nanosecond pulsed electric fields. BIOMEDICAL OPTICS EXPRESS 4105 2015 Vol. 6, No. 10;
86 A resilient formin-derived cortical actin meshwork in the rear drives actomyosin-based motility in 2D confinement. Nature Communications 6, Article number: 8496, 29 September 2015;
85 Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control. JOVE 3/30/2015, Issue 97;
84 Apparatus and Method for Producing Specimens for Electron Microscopy. patent US 20140360286 A1;
83 Evolution of Network Synchronization during Early Epileptogenesis Parallels Synaptic Circuit Alterations. The Journal of Neuroscience, 8 July 2015, 35(27): 9920-9934;
82 Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides Cell. Cell 2015 vol.162 issue 1, p84-95;
78 Real-Time Imaging of Discrete Exocytic Events Mediating Surface Delivery of AMPA Receptors. The Journal of Neuroscience, 10 October 2007, 27(41): 11112-11121;
81 Potentiation of NMDA receptor-mediated transmission in striatal cholinergic interneurons. Front. Cell. Neurosci., 09 April 2015;
80 Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques. Nature Protocols 11, 1067–1080 (2016);
79 Measurement of DCF fluorescence as a measure of reactive oxygen species in murine islets of Langerhans. Anal. Methods, 2014,6, 3019-3024;
78 Conformational biosensors reveal adrenoceptor signalling from endosomes. Nature. 2013 Mar 28; 495(7442);
77 Real-Time Imaging of Discrete Exocytic Events Mediating Surface Delivery of AMPA Receptors. The Journal of Neuroscience, 10 October 2007, 27(41): 11112-11121;
76 Spectroscopic THz near-field microscope. Optics Express Vol. 16, Issue 5, pp. 3430-3438 (2008);
75 Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control. J. Vis. Exp. (97), e52620;
74 Capture and release of particles from liquid samples;
73 METHODS OF GENERATING ENGINEERED INNERVATED TISSUE AND USES THEREOF;
72 Live Imaging Kidney Development in Zebrafish. Methods in Molecular Biology Volume: 886 Pub. Date: May-31-2012 Page Range: 55-70;
71 Droplet-based electro-coalescence for probing threshold disjoining pressure. Lab Chip, 2015,15, 2018-2024;
70 Dopamine-Mediated Autocrine Inhibitory Circuit Regulating Human Insulin Secretion in Vitro. Mol Endocrinol. 2012 Oct; 26(10): 1757–1772;
69 Alternative Translation Initiation of Human Regulators of G-Protein Signaling-2 Yields a Set of Functionally Distinct Proteins. Molecular Pharmacology January 2008 vol. 73 no. 1 1-11 ;
68 Elastic Instability of a Crystal Growing on a Curved Surface. 7 February 2014, Science 343, 634 (2014);
67 Bacillus subtilis chromosome organization oscillates between two distinct pattern. PNAS September 2, 2014 vol. 111 no. 35 12877–12882;
66 The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I. Biochem. J. (2014) 463 (257–270);
65 Potentiation of NMDA receptor-mediated transmission in striatal cholinergic interneurons. Front. Cell. Neurosci., 09 April 2015;
64 Visual-Induced Excitation Leads to Firing Pauses in Striatal Cholinergic Interneurons. The Journal of Neuroscience, 3 August 2011, 31(31): 11133-11143;
63 Connexin40 Imparts Conduction Heterogeneity to Atrial Tissue. Circ Res. 2008;103:1001-1008;
62 Investigating G protein-coupled receptor endocytosis and trafficking by TIR-FM. Methods Mol Biol. 2011; 756: 325–332;
61 Human sensory neurons: membrane properties and sensitization by inflamatory mediators. PAIN 155 (2014) 1861-1870;
60 Alterations in Ovarian Cancer Cell Adhesion Drive Taxol Resistance by Increasing Microtubule Dynamics in a FAK-dependent Manner. Nature, Scientific Reports, 17 April 2015, Volume:5, Article number:9529;
59 Measurement of DCF fluorescence as a measure of reactive oxygen species in murine islets of Langerhans. Anal. Methods, 2014,6, 3019-3024,
58a 58b Intracellular temperature mapping with fluorescence-assisted photoacoustic-thermometry. Appl Phys Lett. 2013 May 13; 102(19): 193705,
57, 56, 55, 54, 53, 52, 51, 50, 49, 48, 47, 46, 45, 44, 43, 42, 41, 40, 39, 38, 37, 36, 35, 34, 33, 32, 31, 30, 29, 28, 27, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10

Liquid delivery and perfusion:
55 Circadian control of dopaminergic signaling to the mushroom body regulates 2 sleep through rhythmic Pka-C1 transcription in Drosophila. bioRxiv August 31, 2025;
54 Enhancing Evanescent Wave Coupling of Near-Surface Waveguides with Plasmonic Nanoparticles. Sensors 2023, 23, 3945;
53 Sites of Circadian Clock Neuron Plasticity Mediate Sensory Integration and Entrainment. 2021;
52 Evaluation of Optogenetic Electrophysiology Tools in Human Stem Cell-Derived Cardiomyocytes. Frontiers in Physiology 8 October 2017;
51 A neural network underlying circadian entrainment and photoperiodic adjustment of sleep and activity in Drosophila. Journal of Neuroscience, 36(35), 9084-9096. 2016;
50 Optogenetic Control of Gene Expression in Drosophila. PLOS one, September 18, 2015;
49 Analysis of functional neuronal connectivity in the Drosophila brain J Neurophysiol. 2012 Jul 15; 108(2): 684–696;
48 Differentially timed extracellular signals synchronize pacemaker neuron clocks. PLoS Biol. 2014 September; 12(9);
47 TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine. Nature Communications, ( 2022) 13:6304;
46 Androgenic TRPM8 activity drives sexual dimorphism in a murine model of chronic migraine. Research Square October 19th, 2021;
45 Sites of Circadian Clock Neuron Plasticity Mediate Sensory Integration and Entrainment. 2021;
44 A compact microscope for voltage imaging. Journal of Optics, Volume 24, Number 5 2022;
43 Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage Clamp Fluorometry. Molecular Pharmacology October 3, 2019;
Synchronized Retrovirus Fusion in Cells Expressing Alternative Receptor Isoforms Releases the Viral Core into Distinct Sub-cellular Compartments PLoS Pathogens, Volume 8, Number 5, 2012;
41 Cotransporter-mediated water transport underlying cerebrospinal fluid formation Nature Communicationsvolume 9, Article number: 2167 (2018);
40 A novel inwardly rectifying K+ channel, Kir2.5, is upregulated under chronic cold stress in fish cardiac myocytes. Journal of Experimental Biology 2008 211: 2162-2171;
39 Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel. PLOS Biology December 27, 2017;
38 Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator. J. Vis. Exp. (126), e55698, doi:10.3791/55698 (2017);
37 Fusion of Mature HIV-1 Particles Leads to Complete Release of a Gag-GFP-Based Content Marker and Raises the Intraviral pH. PLoS ONE Volume 8, Number 8 2013;
36 Exocytotic release of ATP by preBφtzinger Complex astrocytes contributes to the hypoxic ventilatory response via a calcium-dependent P2Y1 receptor mechanism;
35 Connectivity, Organization, and Network Coordination of the Drosophila Central Circadian Clock;
34 EFFECT OF ECONAZOLE AND BENZYDAMINE ON SENSORY NEURONS IN CULTURE. JPP No 6/2016 article 06;
33 Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures . PNAS vol. 112 no. 4, 949–956;
32 Optogenetic Control of Gene Expression in Drosophila. PLOS one, September 18, 2015;
31 Spatiotemporal Coding of Individual Chemicals by the Gustatory System. The Journal of Neuroscience, 2 September 2015, 35(35): 12309-12321;
30 Evaluating the Functionality of Conjunctiva Using a Rabbit Dry Eye Model. Journal of Ophthalmology Volume 2016 (2016);
29 Visualization of retrovirus uptake and delivery into acidic endosomes. Biochemical Journal Mar 15, 2011, 434 (3) 559-569;
28 Basolateral and central amygdala differentially recruit and maintain dorsolateral striatumdependent cocaine-seeking habits. NATURE COMMUNICATIONS 14 Dec 2015;
27. Human sensory neurons: membrane properties and sensitization by inflamatory mediators. PAIN 155 (2014) 1861-1870;
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Sample and perfusion chambers:
56 SECM stack imaging and full 3D modelling of asymmetric clusters of live cells/ Electrochimica Acta Volume 538, 20 October 2025;
55 Where in the Tissues of Danio rerio Is More H2O2 Produced During Acute Hypoxia? Sage Journals January 31, 2025;
54 Alternate Splicing Directs PMCA2 to Lysosomes and is Linked to Neurodegeneration. bioRxiv October 2, 2025;
53 Local Chromatin Organization and Net Charge Modulate DNA Glycosylase Eciency in Live Cell. Research Square October 22nd, 2025;
52 Super-Resolution Diffusivity Mapping Reveals Spatial Correlations Between Lateral Mobility and Structural Heterogeneities on Cellular Membranes. bioRXiv April 06, 2025;
51 Lysosomal TPC2 channels disrupt Ca2+ entry and dopaminergic function in models of LRRK2-Parkinsons disease. J Cell Biol (2025) 224 (6);
50 Neural circuit mechanisms underlying context-specific halting in Drosophila. Nature. 2024 Oct 2;634(8032):191–200;
49 Convergent activation of Ca2+ permeability in two-pore channel 2 through distinct molecular routes. SCIENCE SIGNALING, 22 Aug 2023, Vol 16, Issue 799;
48 Analysis of Mouse Brain Sections by Live-cell Time-lapse Confocal Microscopy. Bio-protocol, 05 Apr 2023, 13(7);
47 Degradation Kinetics of Disulfide Cross-Linked Microgels: Real-Time Monitoring by Confocal Microscopy. Gels. 2023 Oct; 9(10): 782;
46 Biomimetic Nanoarchitectures for the Study of T Cell Activation with Single-Molecule Control. 2016;
45 Sites of Circadian Clock Neuron Plasticity Mediate Sensory Integration and Entrainment. 2021;
44. Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA; NATURE COMMUNICATIONS (2020) 11:983
43. Probing Nanoscale Diffusional Heterogeneities in Cellular Membranes through Multidimensional Single-Molecule and Super-Resolution Microscopy; J. Am. Chem. Soc. 2020, 142, 44, 18866–18873
42 Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through ί1 integrin, Src and ERK 1/2. Oncotarget. 2016; 7:47904-47917;
41 2,2,2-Trichloroethanol activates a non-classical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery. JPET December 2, 2009;
40 Dissection of mechanical force in living cells by super-resolved traction force microscopy Nature Protocols volume 12, pages 783–796 (2017);
39 Pivotal Role of Actin Depolymerization in the Regulation of Cochlear Outer Hair Cell Motility Biophysical Jurnal Volume 99, Issue 7, 6 October 2010, Pages 2067-2076;
39 Improved Glass Surface Passivation for Single-Molecule Nanoarrays Langmuir, 2016, 32 (39), pp 10034–10041;
38 Transfection of Cells with DNA Encoding a Visible Fluorescent Protein-Tagged Lipid-Binding Domain Spring Harb Protoc 2017;
37 Pathogen-Related Differences in the Abundance of Presented Antigen Are Reflected in CD4+ T Cell Dynamic Behavior and Effector Function in the Lung. J Immunol published online 15 January 2014;
36 A neural network underlying circadian entrainment and photoperiodic adjustment of sleep and activity in Drosophila. Journal of Neuroscience, 36(35), 9084-9096. 2016;
35 Dissection of mechanical force in living cells by super-resolved ... Proc. Natl. Acad. Sci. USA 113, 2898–2903 (2016).;
34 Unique Hydrophobic Extension of the RGS2 Amphipathic Helix Domain Imparts Increased Plasma Membrane Binding and Function Relative to Other RGS R4/B Subfamily Members. THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 282, NO. 45, pp. 33064–33075, November 9, 2007;
32 Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses. Neuroscience. 2014 June 20; 271: 45–55;
31 Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic ί Cells. The Journal of Biological Chemistry 290, 21376-21392. August 28, 2015;
30 PKCa-Mediated Signals Regulate the Motile Responses of Cochlear Outer Hair Cells. Biophysical Journal Volume 108, Issue 9, 5 May 2015, Pages 2171–2180;
29 Dynamical feature extraction at the sensory periphery guides chemotaxis. eLife 2015;4:e06694;
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Petri dish perfusion:
17 Enhancing Evanescent Wave Coupling of Near-Surface Waveguides with Plasmonic Nanoparticles. Sensors 2023, 23, 3945;
16 Sites of Circadian Clock Neuron Plasticity Mediate Sensory Integration and Entrainment. 2021;
15 Evaluation of Optogenetic Electrophysiology Tools in Human Stem Cell-Derived Cardiomyocytes. Frontiers in Physiology 8 October 2017;
14 A neural network underlying circadian entrainment and photoperiodic adjustment of sleep and activity in Drosophila. Journal of Neuroscience, 36(35), 9084-9096. 2016;
13 Optogenetic Control of Gene Expression in Drosophila. PLOS one, September 18, 2015;
12. Analysis of functional neuronal connectivity in the Drosophila brain J Neurophysiol. 2012 Jul 15; 108(2): 684–696;
11. Differentially timed extracellular signals synchronize pacemaker neuron clocks. PLoS Biol. 2014 September; 12(9);
10. Functional Conservation of Clock Output Signaling between Flies and Intertidal Crabs. Journal of Biological Rhythms, November 30, 2011;
10, 9, 8, 7, 6, 1, 2, 3, 4, 5. CONTROLLED FLOW PERFUSION SYSTEM Perfusion Systems Flow Control Temperature Control Miniature Holders Miniature Manifolds Local Perfusion Small Volume Delivery System Perfusion Chambers for replaceable coverslip Ultra-Thin Imaging Chambers Closed Controlled Environment Chambers & Mini-Incubators Uniform Heating Slide Heaters Chambers, Thin profile, Heated, Perfusion, for AFM and Water Immersion Accessories Low Profile Heated Chambers Imaging, High Resolution Chambers Accessories Chambers with Transparent Uniform Heaters Heated Chambers Open Chambers Thin Sealed Chambers Magnetic & Screw-Type Holders, Miniature Perfusion Accessories, Micro-Manifolds and Tubing micro-Manifolds Miscellaneous Perfusion Pumps Small Volume Delivery Systems Tubing & Fitting Perfusion Chambers Controlled Environment Closed Imaging Chambers CoverSlip Chambers Petri Dish Inserts Perfusion Systems, Fast and Miniature Pinch Valves Perfusion Systems Perfusion Systems, Flow Control Accessories Miniature Perfusion Systems Pressure Micro Injectors - Spritzers 1-Channel Injectors 4, 8-channel Micro Injectors - Spritzers Temperature Controllers, Heating 1-Channel Controller, Low Electrical Noise 2-Channel Temperature Controller Temperature Controllers, Heating & Cooling Bipolar Heating/Cooling Controllers